Genetic recurrence and molecular markers of dyslexia in the Brazilian population

Purpose: to investigate genetic recurrence and molecular markers for dyslexia in two candidate genes the Brazilian population. Methods: a cross-sectional, case-control, observational study, with five single nucleotide polymorphisms (SNPs) studied DYX1C1 KIAA0319 86 subjects 66 controls, matched gender age. SNPs were genotyped using polymerase chain reaction technique real time, distribution of genotypic allelic frequencies between groups was analyzed. Results: it determined that 68% present family history learning difficulties. The gene did not demonstrate an association dyslexia, which found regarding rs9461045 marker gene. Conclusion: problems more than two-thirds group indicating this is important risk factor. An noted, making study first one show Latin America.